would it be possible to use AVB over fast WiFi?
You cannot. You wouldn’t want to anyway due to dropped packets are just part of wifi life. Packets just can’t come in any order for audio.
Looks like there are some significant limitations to using the MOTU in AVB mode on anything later than macOS 10.10… is this still the case? After some rather frustrating attempts to use it via USB, I’m back to Thunderbolt for now. It hasn’t crashed so far.* Seems weird to let a computer that sells for a base price of $699 determine whether I can use my $1499 interface… 
Having said that, this computer is blazingly fast. Mine has the 16Gb RAM option and a 1TB SSD. It is significantly snappier than my 2013 Mac Pro trash can. 
*EDIT: spoke too soon. It crashed on shutdown again this evening. Perusing various interface manufacturer’s support reveals that this is an endemic issue with Thunderbolt interfaces. Focusrite for one suggest a change in security settings before installing any 3rd party driver. MOTU suggest a similar process for some of their interfaces, but not the 1248 and, in fact, following this procedure didn’t help. Crashola.
I was told by a MOTU tech not to connect to the computer with the ether/AVB. Tho you can, it’s not as efficient. It is to be used to chain interfaces. Thunder preferred.
this is how I remember the conversation. Maybe I’m wrong. I’m old
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I’ve been using it that way for over a year, direct via Ethernet. I mean it’s actually listed in the manual as the 1st option for AVB.
I’m really only using it to get multiple tracks from iOS into logic in 1 go and for system audio. That logic session goes elsewhere when I’m done. I haven’t found any issues using it as a standard audio interface
@Scot_Solida what limitations are you seeing?
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Ya I know it’s listed in the manual. That’s why I did it. But the tech at MOTU said it’s not optimal. I asked why it was in the manual. He said cuz you can do……but it’s not optimal. 
Okay…whatever you say man.
I’m just relaying what he told me.
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I wasn’t dissing what you’ve been told. Just relaying my experiences.
Im curious what they say isn’t optimal or any limitations Scot might have found. I haven’t found any downsides in my experiences other than occasionally I have to rediscover the interface after a reboot of the mac.
The iOS devices on the usb end are the main setup of my rig, not the mac.
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MOTU’s tech note: MOTU.com - Limitations Regarding Direct AVB Audio Connection to a Mac
It’s the last two points that are the most concerning - I can live with higher latencies, but all of my existing projects (and collaborations) are 24/44.1.
Ideally, the thunderbolt issue will be fixed.
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Something to do with the ether cable. Which to me doesn’t make sense cuz how is that diff vs chaining interfaces.
They said it’s best use is for long cable runs.
I dunno. 
Ah. I thought u meant more than those.
If the latency thing is concerning, I can say it’s been under 10ms round trip if that helps.
I haven’t really needed to do any configuration in audiomidi setup. That possibly might be if using multiple interfaces?
The midi thing is only an issue if the motu is also your midi interface
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The long cable runs I get, but it’s still limited to the length of a standard Ethernet cable run (about 300’).
Jesus…300’!
Most of my cables are 6’…if that 
Right? The eithernet cable I have between the mac and the motu is less than 200cm
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Like I said, latency isn’t my biggest concern, but no 44.1kHz is. My sound design work, collaborations, and other tasks require the ability to record and playback at all commonly used sampling rates.
Over time I gradually started using 24/48. I don’t think it was by choice either, just that most things that started being the default. I never bought into the super high sample rates thing, and things that use higher bitrates/sample rates as default make me hesitate switching for the same reasons you state.
You probably have far more uses for an audio interface than I do.
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I’ve been doing 24/48
You think 16/44 is better?
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No. But some jobs (and samplers) require 16-bit/44.1 or 24-bit/44.1, other require 48kHz. I need to be able to freely switch between them as needed.
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I wish I had an M1 to test with for you or screenshot my setup.
(Waiting for that m2…I skip rev1 stuff from apple as rev1 things get fazed out quickly for rev2)
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I want them to announce apple silicon desktops! Then, I get hired, and get a new computer for werk. That’s what I’d like 
But I still want them to announce a desktop!